Small Multitarget Molecules Incorporating the Enone Moiety

Studies on incorporating small fluorescent molecules into PAMAM dendrimers.

Dendrimers are a relatively new class of polymer, with well-defined molecular structures. They are synthesized from a polyfunctional core by adding branched monomers that react with the functional groups of the core, in turn leaving end groups that can react again. This results in a large number of reactive terminal groups that increases after each cycle or " generation ". The structure of a gi...

INTERACTION OF PROTEINS WITH SMALL MOLECULES

Applications of Small Molecules in Muscle Tissue Engineering

Introduction: Skeletal muscles account for about 40% of the total body weight. Every year, hundreds of people lose at least part of their muscle tissue due to illness, war, and accidents. This can lead to disruption of activities such as breathing, movement, and social life. To this end, various therapeutic strategies such as medication therapy, cell therapy and tissue transplantation have been...

small molecules as protein-proteininteraction inhibitors

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Kernels for small molecules

2 Graph kernels 2 2.1 Implementation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2.2 The Spectrum Kernel . . . . . . . . . . . . . . . . . . . . . . . . 2 2.3 The Tanimoto Kernel . . . . . . . . . . . . . . . . . . . . . . . . 3 2.4 The MinMax Kernel . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.5 The Marginalized Kernel . . . . . . . . . . . . . . . . . . . . . . . 3 2.6 ...